{"id":100,"date":"2025-09-04T12:09:05","date_gmt":"2025-09-04T10:09:05","guid":{"rendered":"https:\/\/www.oncovirlab.hr\/?page_id=100"},"modified":"2025-10-06T16:12:30","modified_gmt":"2025-10-06T14:12:30","slug":"about-us","status":"publish","type":"page","link":"https:\/\/www.oncovirlab.hr\/en\/about-us\/","title":{"rendered":"About us"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"100\" class=\"elementor elementor-100\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fda1ba4 e-flex e-con-boxed e-con e-parent\" data-id=\"fda1ba4\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1fd0cbd3 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"1fd0cbd3\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\"><\/br>About us<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7736b7b8 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"7736b7b8\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInUp&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Our goal is to investigate immunological mechanisms, advance biomedical knowledge, and contribute to the development of effective therapies and vaccines.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4967880 e-flex e-con-boxed e-con e-parent\" data-id=\"4967880\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;background_motion_fx_motion_fx_scrolling&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_effect&quot;:&quot;yes&quot;,&quot;background_motion_fx_translateY_speed&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:4,&quot;sizes&quot;:[]},&quot;background_motion_fx_translateY_affectedRange&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:{&quot;start&quot;:0,&quot;end&quot;:100}},&quot;background_motion_fx_devices&quot;:[&quot;widescreen&quot;,&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;]}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-07a6693 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"07a6693\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6de2144 elementor-widget elementor-widget-text-editor\" data-id=\"6de2144\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"142\" data-end=\"611\"><span style=\"font-weight: 400;\">The Oncovirlab team is a group of scientists and experts based at the Centre for Research and Knowledge Transfer in Biotechnology, University of Zagreb (Rockefellerova 10, 10000 Zagreb), dedicated to developing oncolytic viral preparations for the treatment of cancer in humans and animals. Our inspiration for pursuing this line of therapy stems from a successfully conducted case of self-treatment of human breast cancer within our group (link) <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39339989\/\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span><\/span><span style=\"font-weight: 400;\">).<\/span><\/p><p data-start=\"142\" data-end=\"611\">Our strengths lie in expertise in immunology, virology, and biochemistry, a strong commitment to scientific excellence, an interdisciplinary approach, and a passion for bringing scientific discoveries closer to people in order to address modern healthcare challenges.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a73b4e e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"3a73b4e\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInRight&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bef72bd elementor-widget elementor-widget-image\" data-id=\"bef72bd\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1833\" height=\"1281\" src=\"https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807.webp\" class=\"attachment-full size-full wp-image-1222\" alt=\"\" srcset=\"https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807.webp 1833w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807-300x210.webp 300w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807-1024x716.webp 1024w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807-768x537.webp 768w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807-1536x1073.webp 1536w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8807-18x12.webp 18w\" sizes=\"(max-width: 1833px) 100vw, 1833px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b709df1 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"b709df1\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInLeft&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d41e999 elementor-widget elementor-widget-image\" data-id=\"d41e999\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"800\" height=\"849\" src=\"https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796-965x1024.webp\" class=\"attachment-large size-large wp-image-1211\" alt=\"\" srcset=\"https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796-965x1024.webp 965w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796-283x300.webp 283w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796-768x815.webp 768w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796-11x12.webp 11w, https:\/\/www.oncovirlab.hr\/wp-content\/uploads\/2025\/10\/Oncovirlab_8796.webp 1280w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b900b6b e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"b900b6b\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dd99ce7 elementor-widget elementor-widget-text-editor\" data-id=\"dd99ce7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The Oncovirlab research team\u2019s expertise includes genotyping of RNA viruses, particularly paramyxoviruses and pneumoviruses<span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"#reference\"><sup>1-7<\/sup><\/a><\/span>. In addition, our scientists are specialized in the development and optimization of upstream biotechnological processes<span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"#reference\"><sup>8<\/sup><\/a><\/span> and biological assays in virology and immunology<span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"#reference\"><sup>1,9-13<\/sup><\/a><\/span>, as well as in the design of downstream purification and concentration procedures for biologically active macromolecules<span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"#reference\"><sup>14-19<\/sup><\/a><\/span> and their translation into end products.<\/p><p>We place special emphasis on knowledge transfer and collaboration \u2013 both within the academic community and with industry partners and public institutions. In this way, we contribute to the application of scientific discoveries in practice, foster the development of innovative therapeutic approaches, and ensure that research outcomes have a real impact on society.<\/p><p>Our laboratory is also a place for educating new generations of scientists, where students and young researchers have the opportunity to participate in projects, gain hands-on experience, and develop critical scientific thinking. In doing so, we actively contribute to the development of biomedical expertise in Croatia and beyond.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-74dcc27 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"74dcc27\" data-element_type=\"container\" id=\"reference\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5e084ee elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5e084ee\" data-element_type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01a4a1e elementor-widget elementor-widget-text-editor\" data-id=\"01a4a1e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h3>REFERENCES<\/h3><ol><li><span style=\"font-weight: 400;\">Ravli\u0107 S, He\u0107imovi\u0107 A, Kurtovi\u0107 T, et al. Is better standardization of therapeutic antibody quality in emerging diseases epidemics possible? Front Immun 2022;13:816159. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2022.816159\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Ljubin-Sternak S, Slovic A, Mijac M, Jurkovic M, Forcic D, Ivkovic-Jurekovic I, Tot T, Vranes J. Prevalence and molecular characterization of human bocavirus detected in Croatian children with respriratory infection. Viruses-Basel 2021;13:1728. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.3390\/v13091728\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Ljubin-Sternak S, Mestrovic T, Ivkovic-Jurekovic I, Kolaric B, Slovic A, Forcic D, Tot T, Mijac M, Vranes J. The emerging role of rhinoviruses in lower respiratory tract infections in children \u2013 clinical and molecular epidemiological study from Croatia, 2017-2019. Front Microbiol 2019;10:2737. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.3389\/fmicb.2019.02737\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Jagusic M, Slovic A, Ivancic-Jelecki J, Ljubin-Sternak S, Vilibic-Cavlek T, Tabain I, Forcic D. Molecular epidemiology of human respiratory syncytial virus and human metapneumovirus in hospitalized children with acute respiratory infections in Croatia, 2014-2017. Infect Gen Evol 2019;76:104039. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.meegid.2019.10403\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Kosutic-Gulija T, Slovic A, Ljubin-Sternak S, Mlinaric-Galinovic G, Forcic D. Genetic analysis of human parainfluenza virus type 3 obtained in Croatia, 2011-2015. J Med Microbiol 2017;66:502-510. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1099\/jmm.0.000459\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Santak M, Slovic A, Ljubin-Sternak S, Galinovic GM, Forcic D. Genetic diversity among human parainfluenza virus type 2 isolated in Croatia between 2011 and 2014. J Med Virol 2016;88:1733-1741. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1002\/jmv.24532\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Jin L, Orvell C, Myers M, Rota PA, Nakayama T, Forcic D, Hiebert J, Brown KE. Genomic diversity of mumps virus and global distribution of the 12 genotypes. Rev Med Virol 2015;25:85-101. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1002\/rmv.1819\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Markusic M, Pavlovic N, Santak M, Maric G, Kotarski Lj, Forcic D. Critical factors for the replication of mumps virus in primary chicken embryo fibroblasts defined by the use of design of experiments (DoE). Appl Microbiol Biotechnol 2013;97:1533-1541. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1007\/s00253-012-4394-4\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Kutle L, Pavlovic N, Dorotic M, Zadro I, Kapustic M, Halassy B. Robustness testing of live attenuated rubella vaccine potency assay using fractional factorial design of experiments. Vaccine 2010;28:5497-5502. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.vaccine.2010.04.111\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Forcic D, Kosutic-Gulija T, Santak M, Jug R, Ivancic-Jelecki J, Markusic M, Mazuran R. Comparison of mumps virus potency estimates obtained by 50% cell culture infective dose assay and plaque assay. Vaccine 2010;28:1887-1892. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.vaccine.2009.11.049\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Halassy B, Kurtovic T, Brgles M, Lang Balija M, Forcic D. Factors influencing preclinical in vivo evaluaton of mumps vaccine strain immunogenicity. Hum Vacc Immunother 2015;11:2446-2454. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1080\/21645515.2015.1062191\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Halassy B, Kurtovic T, Lang Balija M, Brgles M, Tunjic M, Sviben D. Concept of sample-specific correction of immunoassay results for precise and accurate IgG quantification in horse plasma. J Pharm Biomed Anal 2019;164:276-282. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.jpba.2018.10.02\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Ravlic S, Kurtovic T, Krajinovic LC, Hecimovic A, Milos M, Lukacevic SM, Markotic A, Halassy B. What can neutralizing anibodies tell us about the quality of immunity in COVID-19 convalescents and vaccinees? Hum Vacc Immunother 2023;19:2270310. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1080\/21645515.2023.2270310\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Ravlic S, Brgles M, Hirsl L, Jonjic S, Halassy B. Production- and purification-relevant properties of human and murine cytomegalovirus. Viruses-Basel 2021;13:2481. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.3390\/v13122481\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Brgles M, Sviben D, Forcic D, Halassy B. Nonspecific native elution of proteins and mumps virus in immunoaffinity chromatography. J Chromatogr A 2016;1447:107-114. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.chroma.2016.04.022\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Sviben D, Forcic D, Ivancic-Jelecki J, Halassy B, Brgles M. Recovery of infective virus particles in ion-exchange and hydrophobic interacion monolith chromatography is influenced by particle charge and total-to-infective particle ratio. J Chromatogr B 2017;1054:10-19. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1016\/j.jchromb.2017.04.015\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Kurtovi\u0107 T, Lang Balija M, Brgles M, Sviben D, Tunjic M, Cajner H, Marchetti-Deschmann M, Allmaier G, Halassy B. Refinement strategy for antivenom preparation of high yield and quality. PLoS Negl Trop Dis 2019;13: e0007431. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1371\/journal.pntd.0007431\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li><span style=\"font-weight: 400;\">Kurtovic T, Ravlic S, Stimac A. Lukacevic SM, Kazazic S, Halassy B. Efficient and sustainable platform for preparation of a high-quality immunoglobulin G as an urgent treatment option uring emerging virus outbreaks. Front Immun 2022;13: 889736. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.3389\/fimmu.2022.889736\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/span><\/li><li>Kurtovic T, Brgles M, Lang Balija M, Steinberger S, Sviben D, Marchetti-Deschmann M, Halassy B. Streamlined downstream process for efficient and sustainable F(ab')2 antivenom preparation. J Venom Anim Toxins Incl Trop Dis 2020;26:e20200025. Link to more information <span style=\"color: #00ccff;\"><a style=\"color: #00ccff;\" href=\"https:\/\/doi.org\/10.1590\/1678-9199-JVATITD-2020-0025\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span>.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>O nama Na\u0161 je cilj istra\u017eiti imunolo\u0161ke mehanizme, unaprijediti biomedicinska znanja i pridonijeti razvoju u\u010dinkovitih terapija i cjepiva. Oncovirlab tim \u010dini skupina znanstvenika i stru\u010dnjaka zaposlenih u Centru za istra\u017eivanje i prijenos znanja u biotehnologiji Sveu\u010dili\u0161ta u Zagrebu na adresi Rockefellerova 10, 10000 Zagreb, posve\u0107enih razvoju onkoliti\u010dkih virusnih pripravaka za lije\u010denje raka u ljudi i [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-100","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.0 (Yoast SEO v26.0) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>O nama<\/title>\n<meta name=\"description\" content=\"Saznajte vi\u0161e o laboratoriju koji razvija inovativne metode viroterapije i napredna istra\u017eivanja u podru\u010dju tumora u Hrvatskoj.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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