{"id":100,"date":"2025-09-04T12:09:05","date_gmt":"2025-09-04T10:09:05","guid":{"rendered":"https:\/\/www.oncovirlab.hr\/?page_id=100"},"modified":"2025-10-06T16:12:30","modified_gmt":"2025-10-06T14:12:30","slug":"about-us","status":"publish","type":"page","link":"https:\/\/www.oncovirlab.hr\/en\/o-nama\/","title":{"rendered":"About us"},"content":{"rendered":"\t\t
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<\/br>O nama<\/h1>\t\t\t\t<\/div>\n\t\t\t\t
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Na\u0161 je cilj istra\u017eiti imunolo\u0161ke mehanizme, unaprijediti biomedicinska znanja i pridonijeti razvoju u\u010dinkovitih terapija i cjepiva.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Oncovirlab tim \u010dini skupina znanstvenika i stru\u010dnjaka zaposlenih u Centru za istra\u017eivanje i prijenos znanja u biotehnologiji Sveu\u010dili\u0161ta u Zagrebu na adresi Rockefellerova 10, 10000 Zagreb, posve\u0107enih razvoju onkoliti\u010dkih virusnih pripravaka za lije\u010denje raka u ljudi i \u017eivotinja. Inspiraciju za razvoj ove vrste lije\u010denja crpimo iz\u00a0 uspje\u0161no provedenog samolije\u010denja ljudskog raka dojke unutar na\u0161e grupe (poveznica ovdje<\/a><\/span><\/span>).<\/span><\/p>

Na\u0161e snage le\u017ee u stru\u010dnosti u podru\u010dju imunologije, virologije i biokemije, ustrajnom inzistiranju na znanstvenoj izvrsnosti, interdisciplinarnom pristupu te strasti da znanstvena otkri\u0107a pribli\u017eimo ljudima i odgovorimo na suvremene zdravstvene izazove.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Ekspertiza istra\u017eiva\u010dkog tima Oncovirlab-a obuhva\u0107a genotipizaciju RNK virusa, posebice paramiksovirusa i pneumovirusa1-7<\/sup><\/a><\/span>. Osim toga, na\u0161i znanstvenici specijalizirani su za razvoj i optimizaciju uzvodnih (eng. \u201cupstream\u201c) biotehnolo\u0161kih procesa8<\/sup><\/a><\/span> i biolo\u0161kih testova u virologiji i imunologiji1,9-13<\/sup><\/a><\/span>, kao i dizajn nizvodnih (eng.\u201cdownstream\u201c) postupaka pro\u010di\u0161\u0107avanja i koncentriranja biolo\u0161ki aktivnih makromolekula14-19<\/sup><\/a><\/span> te njihovo prevo\u0111enje u konkretne proizvode.<\/p>

Posebnu va\u017enost pridajemo transferu znanja i suradnji \u2013 kako unutar akademske zajednice, tako i s industrijskim partnerima te javnim institucijama. Na taj na\u010din doprinosimo primjeni znanstvenih otkri\u0107a u praksi, poti\u010demo razvoj inovativnih terapijskih pristupa i osiguravamo da rezultati istra\u017eivanja imaju stvaran utjecaj na dru\u0161tvo.<\/p>

Na\u0161 laboratorij je ujedno i mjesto edukacije novih generacija znanstvenika, gdje studenti i mladi istra\u017eiva\u010di imaju priliku sudjelovati u istra\u017eivanjima, stjecati prakti\u010dna znanja i razvijati kriti\u010dko znanstveno razmi\u0161ljanje. Time aktivno doprinosimo razvoju biomedicinskog kadra u Hrvatskoj i izvan nje.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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REFERENCE<\/h3>
  1. Ravli\u0107 S, He\u0107imovi\u0107 A, Kurtovi\u0107 T, et al. Is better standardization of therapeutic antibody quality in emerging diseases epidemics possible? Front Immun 2022;13:816159. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  2. Ljubin-Sternak S, Slovic A, Mijac M, Jurkovic M, Forcic D, Ivkovic-Jurekovic I, Tot T, Vranes J. Prevalence and molecular characterization of human bocavirus detected in Croatian children with respriratory infection. Viruses-Basel 2021;13:1728. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  3. Ljubin-Sternak S, Mestrovic T, Ivkovic-Jurekovic I, Kolaric B, Slovic A, Forcic D, Tot T, Mijac M, Vranes J. The emerging role of rhinoviruses in lower respiratory tract infections in children – clinical and molecular epidemiological study from Croatia, 2017-2019. Front Microbiol 2019;10:2737. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  4. Jagusic M, Slovic A, Ivancic-Jelecki J, Ljubin-Sternak S, Vilibic-Cavlek T, Tabain I, Forcic D. Molecular epidemiology of human respiratory syncytial virus and human metapneumovirus in hospitalized children with acute respiratory infections in Croatia, 2014-2017. Infect Gen Evol 2019;76:104039. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  5. Kosutic-Gulija T, Slovic A, Ljubin-Sternak S, Mlinaric-Galinovic G, Forcic D. Genetic analysis of human parainfluenza virus type 3 obtained in Croatia, 2011-2015. J Med Microbiol 2017;66:502-510. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  6. Santak M, Slovic A, Ljubin-Sternak S, Galinovic GM, Forcic D. Genetic diversity among human parainfluenza virus type 2 isolated in Croatia between 2011 and 2014. J Med Virol 2016;88:1733-1741. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  7. Jin L, Orvell C, Myers M, Rota PA, Nakayama T, Forcic D, Hiebert J, Brown KE. Genomic diversity of mumps virus and global distribution of the 12 genotypes. Rev Med Virol 2015;25:85-101. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  8. Markusic M, Pavlovic N, Santak M, Maric G, Kotarski Lj, Forcic D. Critical factors for the replication of mumps virus in primary chicken embryo fibroblasts defined by the use of design of experiments (DoE). Appl Microbiol Biotechnol 2013;97:1533-1541. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  9. Kutle L, Pavlovic N, Dorotic M, Zadro I, Kapustic M, Halassy B. Robustness testing of live attenuated rubella vaccine potency assay using fractional factorial design of experiments. Vaccine 2010;28:5497-5502. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  10. Forcic D, Kosutic-Gulija T, Santak M, Jug R, Ivancic-Jelecki J, Markusic M, Mazuran R. Comparison of mumps virus potency estimates obtained by 50% cell culture infective dose assay and plaque assay. Vaccine 2010;28:1887-1892. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  11. Halassy B, Kurtovic T, Brgles M, Lang Balija M, Forcic D. Factors influencing preclinical in vivo evaluaton of mumps vaccine strain immunogenicity. Hum Vacc Immunother 2015;11:2446-2454. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  12. Halassy B, Kurtovic T, Lang Balija M, Brgles M, Tunjic M, Sviben D. Concept of sample-specific correction of immunoassay results for precise and accurate IgG quantification in horse plasma. J Pharm Biomed Anal 2019;164:276-282. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  13. Ravlic S, Kurtovic T, Krajinovic LC, Hecimovic A, Milos M, Lukacevic SM, Markotic A, Halassy B. What can neutralizing anibodies tell us about the quality of immunity in COVID-19 convalescents and vaccinees? Hum Vacc Immunother 2023;19:2270310. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  14. Ravlic S, Brgles M, Hirsl L, Jonjic S, Halassy B. Production- and purification-relevant properties of human and murine cytomegalovirus. Viruses-Basel 2021;13:2481. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  15. Brgles M, Sviben D, Forcic D, Halassy B. Nonspecific native elution of proteins and mumps virus in immunoaffinity chromatography. J Chromatogr A 2016;1447:107-114. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  16. Sviben D, Forcic D, Ivancic-Jelecki J, Halassy B, Brgles M. Recovery of infective virus particles in ion-exchange and hydrophobic interacion monolith chromatography is influenced by particle charge and total-to-infective particle ratio. J Chromatogr B 2017;1054:10-19. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  17. Kurtovi\u0107 T, Lang Balija M, Brgles M, Sviben D, Tunjic M, Cajner H, Marchetti-Deschmann M, Allmaier G, Halassy B. Refinement strategy for antivenom preparation of high yield and quality. PLoS Negl Trop Dis 2019;13: e0007431. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  18. Kurtovic T, Ravlic S, Stimac A. Lukacevic SM, Kazazic S, Halassy B. Efficient and sustainable platform for preparation of a high-quality immunoglobulin G as an urgent treatment option uring emerging virus outbreaks. Front Immun 2022;13: 889736. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/span><\/li>
  19. 19. Kurtovic T, Brgles M, Lang Balija M, Steinberger S, Sviben D, Marchetti-Deschmann M, Halassy B. Streamlined downstream process for efficient and sustainable F(ab’)2 antivenom preparation. J Venom Anim Toxins Incl Trop Dis 2020;26:e20200025. Poveznica sa vi\u0161e informacija ovdje<\/a><\/span>.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

    O nama Na\u0161 je cilj istra\u017eiti imunolo\u0161ke mehanizme, unaprijediti biomedicinska znanja i pridonijeti razvoju u\u010dinkovitih terapija i cjepiva. Oncovirlab tim \u010dini skupina znanstvenika i stru\u010dnjaka zaposlenih u Centru za istra\u017eivanje i prijenos znanja u biotehnologiji Sveu\u010dili\u0161ta u Zagrebu na adresi Rockefellerova 10, 10000 Zagreb, posve\u0107enih razvoju onkoliti\u010dkih virusnih pripravaka za lije\u010denje raka u ljudi i […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-100","page","type-page","status-publish","hentry"],"yoast_head":"\nO nama<\/title>\n<meta name=\"description\" content=\"Saznajte vi\u0161e o laboratoriju koji razvija inovativne metode viroterapije i napredna istra\u017eivanja u podru\u010dju tumora u Hrvatskoj.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oncovirlab.hr\/en\/about-us\/\" \/>\n<meta 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